Dr. med. Olaf Schmidt

Facharzt für Innere Medizin, Schwerpunkt Pneumologie

Randomized, Double-Blind, Dose-Finding Study for Tiotropium when Added to Olodaterol, Administered via the Respimat® Inhaler in Patients with Chronic Obstructive Pulmonary Disease; R Aalbers, MR Maleki-Yazdi, A Hamilton, S Waitere-Wijker, Y Zhao, VC Amatto, O Schmidt, L Bjermer; Adv Ther. 2015 Sep;32(9):809-22. Adv Ther (2015) 32:809-822

Tiotropium + olodaterol shows clinically meaningful improvements in quality of life; D Singh, GT Ferguson, J Bolitschek, L Grönke, C Hallmann, N Bennett, R Abrahams, O Schmidt, L Bjermer; Respir Med. 2015 Oct;109(10):1312-9

Tiotropium or salmeterol as add-on therapy to inhaled corticosteroids for patients with moderate symptomatic asthma: two replicate, double-blind, placebo-controlled, parallel-group, active-comparator, randomised trials; HAM Kerstjens, TB Casale, ER Bleecker, EO Meltzer, E Pizzichini, O Schmidt, M Engel, LJ Bour, CB Verkleij, P Moroni-Zentgraf, ED Bateman; Lancet Respir Med. 2015;3(5):367-376

Anforderungen an die moderne Inhalationstherapie; O. Schmidt; Medizin Report aktuell Nr. 411166 in: PneumoNews 1/2015

Effects of tiotropium + olodaterol versus tiotropium or placebo by COPD disease severity and previous treatment history in the OTEMTO studies; D Singh, M Gaga, O Schmidt, L Bjermer, L Grönke, F Voß, GT Ferguson; Respiratory Research. 2016 Jun; 17:73

Real-life effectiveness of asthma treatment with a fixed-dose fluticasone/formoterol pressurised metered-dose inhaler e Results from a non-interventional study; O. Schmidt , W. Petro , G. Hoheisel , F. Kanniess , P. Oepen , B. Langer-Brauburger; Respiratory Medicine 131 (2017) 166e174

Tiotropium add-on therapy improves lung function in children with symptomatic moderate asthma; Christian Vogelberg, Michael Engel, István Laki, Jonathan A. Bernstein, Olaf Schmidt, Georges El Azzi, Petra Moroni-Zentgraf, Ralf Sigmund and Eckard Hamelmann; The Journal of Allergy an Clinical Immunology / In Practice / 2018

Spiroergometrie kompakt – Physiologie, Durchführung und Auswertung / Guidance to the Interpretation of Cardiopulmonary Exercise; T. Glaab, O. Schmidt, J. Fritsch; Georg Thieme Verlag KG Stuttgart · New York; Testing Pneumologie 2020; 74(02): 88-102 DOI: 10.1055/a-1069-0611

German Regional Variation of Acute and High Oral Corticosteroid Use for Asthma; Cassandra Nan, Olaf Schmidt, Robert Lindner, Yasemin Ilgin, Thomas Schultz, Lykke Hinsch Gylvin & Eugene R. Bleecker; Journal of Asthma; 01-2021; DOI: 10.1080/02770903.2021.1878532

Prevalence of Patients with Uncontrolled Asthma Despite NVL/GINA Step 4/5 Treatment in Germany; Karl-Christian Bergmann, Dirk Skowasch, Hartmut Timmermann, Robert Lindner, Johann Christian Virchow, Olaf Schmidt, Dirk Koschel, Claus Neurohr, Sebastian Heck, Katrin Milger; Journal of Asthma and Allergy; 2022:15; Dovepress

Real-World Treatment of Patients Newly Diagnosed with Chronic Obstructive Pulmonary Disease: A Retrospective German Claims Data Analysis; Roland Buhl, Thomas Wilke, Nils Picker, Olaf Schmidt, Marlene Hechtner, Anke Kondla, Ulf Maywald, Claus F Vogelmeier; International Journal of Chronic Obstructive Pulmonary Disease 2022:17 2355–2367; Dovepress

Treatment situation of patients with uncontrolled GINA 4 or 5 asthma in Germany; H Timmermann, K Milger, J C Virchow, O Schmidt, K C Bergmann, D Koschel, C Neurohr, F Scholz, R Lindner, S Heck, D Skowasch; European Respiratory Journal 2022 60: 244; DOI: 10.1183/13993003.congress-2022.244

Bronchodilator reversibility in the GAN severe asthma cohort; K Milger, D Skowasch, E Hamelmann, C Mümmler, M Idzko, M Gappa, M Jandl, C Körner-Rettberg, R Ehmann, O Schmidt, C Taube, A Holtdirk, H Timmermann, R Buhl, S Korn; Pubmed; PMID: 36000830; DOI: 10.18176/jiaci.0850

Fixed-dose combination fluticasone/formoterol for asthma treatment in a real-world setting: meta-analysis of exacerbation rates and asthma control; Alberto Papi, Murtaza Qasuri, Ernestine Chung, Mohamed Abdelbaset, Mohamed Aly Moussa, Vibeke Backer, Olaf Schmidt & Omar Usmani; European Clinical Respiratory Journal Feb 2023, 10:1, 2174642, DOI: 10.1080/20018525.2023.2174642

Experiences with digital care of patients with chronic and acute lung diseases during the SARS-CoV-2 pandemic; Marcel Braun, Olaf Schmidt, Thomas Schultz, Holger Woehrle, Martina Große Sundrup, Christoph Schöbel; Pubmed; PMID: 35181796; PMCID: PMC8856116; DOI: 10.1007/s00108-022-01266-3

S2k-Leitlinie zur fachärztlichen Diagnostik und Therapie von Asthma 2023 herausgegeben von der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V.; Diagnosis and treatment of asthma: a guideline for respiratory specialists 2023; published by the German Respiratory Society (DGP) e.V.;
Autorinnen/Autoren: Marek Lommatzsch, Carl-Peter Criée, Carmen C. M. de Jong, Monika Gappa, Christian Geßner, Michael Gerstlauer, Nina Hämäläinen, Peter Haidl, Eckard Hamelmann, Fritz Horak, Marco Idzko, Atanas Ignatov, Andreas Rembert Koczulla, Stephanie Korn, Michael Köhler, Christiane Lex, Jochen Meister, Katrin Milger-Kneidinger, Dennis Nowak, Monika Nothacker, Oliver Pfaar, Wolfgang Pohl, Alexandra M. Preisser, Klaus F. Rabe, Josef Riedler, Olaf Schmidt, Jens Schreiber, Antje Schuster, Maren Schuhmann, Thomas Spindler, Christian Taube, Johann Christian Virchow, Christian Vogelberg, Claus Franz Vogelmeier, FelixWantke, Wolfram Windisch, Heinrich Worth, Angela Zacharasiewicz, Roland Buhl; Veröffentlichung 03-2023
Bei AWMF online – 03-2023
Bei Thieme Pneumologie – 07-2023

Response to Biologics and Clinical Remission in the Adult German Asthma Net Severe Asthma Registry Cohort; Katrin Milger , Hendrik Suhling , Dirk Skowasch, Annette Holtdirk, Nikolaus Kneidinger, Jürgen Behr, Hartmut Timmermann, Christian Schulz, Olaf Schmidt, Rainer Ehmann, Eckard Hamelmann, Marco Idzko, Christian Taube, Marek Lommatzsch, Roland Buhl, Stephanie Korn; Pubmed; 06-2023; PMID: 37301433 DOI: 10.1016/j.jaip.2023.05.047
Bei German Asthma Net e.V.

Characterization of Obesity in Severe Asthma in the German Asthma Net;
Christina Bal, Wolfgang Pohl, Katrin Milger, Dirk Skowasch, Christian Schulz, Monika Gappa, Cordula Koerner-Rettberg, Margret Jandl, Olaf Schmidt, Sonja Zehetmayer, Christian Taube, Eckard Hamelmann, Roland Buhl, Stephanie Korn, Marco Idzko; German Asthma Net (GAN) study group; Pubmed; 07-2023; PMID: 37406803 DOI: 10.1016/j.jaip.2023.06.049
Bei German Asthma Net e.V.

Bronchodilator reversibility in the GAN severe asthma cohort; K Milger, D Skowasch, E Hamelmann, C Mümmler, M Idzko, M Gappa, M Jandl, C Körner-Rettberg, R Ehmann, O Schmidt, C Taube, A Holtdirk, H Timmermann, R Buhl, S Korn; JIACI (Journal of Investigational Allergology and Clinical Immunology) Pubmed; PMID: 36000830 DOI: 10.18176/jiaci.085
Bei German Asthma Net e.V.

Health Care Situation in the Treatment of Uncontrolled GINA Step 4/5 Patients in Germany; Hartmut Timmermann, Katrin Milger, Johann Christian Virchow, Olaf Schmidt, Karl-Christian Bergmann, Dirk Koschel, Claus Neurohr, Florian Scholz, Sebastian Heck, Dirk Skowasch; DovePress, Journal of Asthma and Allergy, 2023:16

Initiation, response assessment, and switch of antibody therapies in patients with severe asthma – A survey among German specialists; Hendrik Suhling, MDa; Dirk Skowasch, MDb; Karl-Christian Bergmann, MDc; Carlo Mümmler, MDd,e; Roland Buhl, MDf; Rainer Ehmanng; Eckard Hamelmann, MDh; Marco Idzko, MDi; Margret Jandlj; Christian Schulzk; Olaf Schmidtl; Christian Taube, MDm; Stephanie Korn, MDn; and Katrin Milger, MDd,e; the GAN registry group; World Allergy Organization Journal, Volume 16, Issue 12, December 2023, 100844

Real-World Characteristics of Patients with Severe Asthma prior to Starting Dupilumab: The ProVENT Study; Stephanie Korn; Olaf Schmidt; Hartmut Timmermann; Henrik Watz; Monika Gappa; Amr Radwan; Lucia De Prado Gómez; Anne Atenhan; Sebastian Barbus; Mayank Thakur; Marek Lommatzsch; Karger 12-2023; Pubmed; 12-2023; PMID: 38086344 DOI: 10.1159/000535390

Dose-finding study for tiotropium and olodaterol when administered in combination via the Respimat® inhaler in patients with COPD; R Aalbers, RM Maleki-Yazdi, A Hamilton, S Waitere-Wijker, A Pivovarova, O Schmidt, L Bjermer;
European Respiratory Society (ERS) – International Congress 2012

Phase III trials to investigate tiotropium as add-on therapy to inhaled corticosteroids for patients with symptomatic asthma: trial design and planned statistical analyses; TB Casale, ER Bleecker, E Meltzer, E Pizzichini, O Schmidt, ED Bateman, M Engel, LJ Bour, CB Verkleij, P Moroni-Zentgraf, HAM Kerstjens;
European Academy of Allergy and Clinical Immunology (EAACI) – International Congress 2013

Tiotropium as add-on therapy to inhaled corticosteroids for patients with symptomatic asthma: lung function and safety;
HAM Kerstjens, ER Bleecker, E Meltzer, TB Casale, E Pizzichini, O Schmidt, ED Bateman, M Engel, LJ Bour, CB Verkleij, P Moroni-Zentgraf;
European Respiratory Society (ERS) – International Congress 2013
Thoracic Society of Australia and New Zealand (TSANZ) – International Congress 2014
Congrès de pneumologie de langue française (CPLF) – International Congress 2014
Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V. (DGP) – Kongress der DGP 2014

Tiotropium as add-on to inhaled corticosteroids significantly improves asthma control as reflected by the ACQ responder rate;
HAM Kerstjens, E Bleecker, E Meltzer, TB Casale, E Pizzichini, O Schmidt, M Engel, LJ Bour, CB Verkjeij, P Moroni-Zentgraf, ED Bateman;
European Respiratory Society (ERS) – International Congress 2013
Thoracic Society of Australia and New Zealand (TSANZ) – International Congress 2014
Congrès de pneumologie de langue française (CPLF) – International Congress 2014
Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V. (DGP) – Kongress der DGP 2014

Asthmabehandlung mit Fluticasonpropionat / Formoterol-Kombination: Zwischenergebnisse einer nicht-interventionellen Studie zur Sicherheit und Wirksamkeit; O Schmidt, F Kanniess, B Langer-Brauburger; Kongress der DGP 2015

FLT9501 ffairness – Studie; flutiform; eine neue Wirkstoffkombination zur Asthmabehandlung nicht- interventionelle Studie zur Sicherheit und Wirksamkeit Ergebnisse Interimsanalyse II; O Schmidt; Kongress der DGP 2015

Once-daily tiotropium Respimat add-on to at least ICS maintenance therapy reduces exacerbation risk in patients with uncontrolled symptomatic asthma; Schmidt O, Halpin D, Bateman E, Paggiaro P, Bleecker E, Engel M, Moroni-Zentgraf P, Schmidt H, Kerstjens H; Posterbeitrag Kongress der DGP 2015

Once-daily tiotropium Respimat add-on to ICS±LABA improves control across asthma severities; O Schmidt, M FitzGerald, H Kerstjens, P Paggiaro, K Ohta, M Ichinose, P Moroni-Zentgraf, M Engel, H Schmidt, ED Bateman; Posterbeitrag Kongress der DGP 2015

Once-daily tiotropium Respimat® is well tolerated and efficacious over 52 weeks in patients with symptomatic asthma in Japan receiving ICS ± LABAs: a randomized, double-blind, placebo-controlled study; O Schmidt, K Ohta, M Ichinose, Y Tohda, M Engel, P Moroni-Zentgraf, S Kunimitsu, W Sakamoto, M Adachi; Posterbeitrag Kongress der DGP 2015

Tiotropium + olodaterol fixed-dose combination shows clinically meaningful improvements in quality of life versus placebo
D Singh, GT Ferguson, J Bolitschek, L Grönke, C Hallmann, N Bennett, R Abrahams, O Schmidt, L Bjermer;
European Respiratory Society (ERS) – International Congress 2015
Canadian Thoracic Society (CTS) – International Congress 2016

Tiotropium + olodaterol shows clinically meaningful improvements in quality of life versus placebo
D Singh, GT Ferguson, J Bolitschek, L Grönke, C Hallman, N Bennett, R Abrahams, O Schmidt, L Bjermer;
The International Primary Care Respiratory Group (IPCRG) – International Congress 2016

Fluticasone propionate/formoterol therapy for asthmatic patients: results of a non-interventional study
O. Schmidt, F. Kanniess, P. Oepen, B. Langer-Brauburger; European Respiratory Society (ERS) – International Congress 2016

Once-daily tiotropium Respimat add-on therapy improves lung function in children with moderate symptomatic asthma
Olaf Schmidt, Eckard Hamelmann, Christian Vogelberg, István Laki, Georges El Azzi, Michael Engel, Petra Moroni-Zentgraf, Helen Finnigan, Mark Vandewalker; European Respiratory Society (ERS) – International Congress 2016

Amélioration cliniquement pertinente de la qualité de vie avec l’association fixe tiotropium + olodaterol versus placebo chez les patients BPCO; P Berger, D Singh, GT Ferguson, J Bolitschek, L Grönke, R Abrahams, O Schmidt, L Bjermer;
Congrès de pneumologie de langue française (CPLF) – International Congress 2016

Safety and tolerability of once-daily tiotropium Respimat add-on therapy in children with moderate symptomatic asthma
Christian Vogelberg, István Laki, Olaf Schmidt, Eckard Hamelmann, Georges El Azzi, Michael Engel, Petra Moroni-Zentgraf, Helen Finnigan, Mark Vandewalker; European Respiratory Society (ERS) – International Congress 2016

Pooled analysis of the efficacy and safety from two non-interventional studies of fluticasone propionate/formoterol pMDI
Vibeke Backer, Olaf Schmidt, Birgit Langer-Brauburger, Tanja Schmidt, Carla Bennett, Dirk Lindner, Susanna Cuadripani, Birgit Grothe, Tim Overend; European Respiratory Society (ERS) – International Congress 2018

Therapie des schweren Asthmas – eine Frage der Präzision: Eine Orientierung aus Theorie und Praxis; Moderne Präzisionstherapie – die Perspektive aus der Praxis – Interaktive Falldiskussionen; O Schmidt, Koblenz; Präsentation Kongress der DGP 2019

Short-Term and Maintenance Oral Corticosteroid Use for German Patients with Asthma; Cassandra Nan, Robert Lindner, Yasemin Ilgin, Thomas Schultz, Olaf Schmidt, Lykke Hinsch Gylvin, Eugene R. Bleecker;
European Respiratory Society (ERS) – International Congress 2019;
Präsentation auf dem Kongress der DGP 2020 wurde pandemiebedingt abgesagt.

Rheinland-Pfalz atmet durch – Telemedizin für eine gesunde Lunge“ – Telemedizin wird von Asthmatikern angenommen und verbessert deren Lebensqualität; O. Schmidt, V. Hanrath;
Posterbeitrag Kongress der DGP 2020 (pandemiebedingt abgesagt)
Posterbeitrag Digitaler DGP Kongress, Juni 2021
Veröffentlichung in Pneumo News, Juni 2021

Real-World Characteristics of Patients Receiving Dupilumab in Routine Clinical Practice in a Multinational, Non-Interventional Study (ProVENT); Marek Lommatzsch, Stephanie Korn, Olaf Schmidt, Hartmut Timmermann, Henrik Watz, Amr Radwan, Lucia de Prado-Gómez, Anne Atenhan, Sebastian Barbus, Mayank Thakur;
Posterbeitrag
European Respiratory Society (ERS) – International (Virtual Congress) 2021
European Academy of Allergy and Clinical Immunology (EACCI)  – Hybrid Congress 2021
16. Deutscher Allergiekongress (DAK) – Dresden 2021

A comparison of clinical characteristics, initiated therapies, and outcomes in newly diagnosed COPD patients in in- and outpatient settings / Vergleich von klinischen Merkmalen, Behandlungsstrukturen und Therapieergebnissen bei Patienten mit stationären oder ambulanten COPD-Initialdiagnosen; Claus F. Vogelmeier, Nils Picker, Thomas Wilke, Marlene Hechtner, Angela Neitz, Ulf Maywald, Olaf Schmidt, Roland Buhl;
Posterbeitrag DGIM Kongress, Wiesbaden, Deutschland, Mai 2022

Prevalence of patients with uncontrolled asthma despite high intensity treatment (NVL/GINA step 4/5) in Germany; Bergmann K-C, Skowasch D, Timmermann H, Lindner R, Virchow J C, Schmidt O, Koschel D, Heck S, Milger K;
Posterbeitrag DGP, Leipzig, Deutschland, 25-28 Mai 2022

Erfahrungen mit Smartphone-basiertem Telemonitoring bei respiratorischen Erkrankungen während der SARS-CoV-2 Pandemie aus ärztlicher Sicht; Braun M, Schmidt O, Schultz T, Junker E, Hastenteufel T, Ackermann E, Defosse K, Schöbel C;
Posterbeitrag DGP, Leipzig, Deutschland, 25-28 Mai 2022;
Veröffentlichung in Der Internist 03/2022

Patienten-relevante Erfahrungen mit Smartphone-basiertem Telemonitoring bei respiratorischen Erkrankungen während der SARS-CoV-2 Pandemie; Braun M, Schmidt O, Schultz T, Woehrle H, Grosse Sundrup M, Schöbel C;
Posterbeitrag DGP, Leipzig, Deutschland, 25-28 Mai 2022;
Veröffentlichung in Der Internist 03/2022

Treatment situation of patients with uncontrolled GINA 4/5 asthma in Germany; Timmermann H., Milger K., Virchow J. Chr., Schmidt O., Bergmann K.-C., Koschel D., Neurohr C., Scholz F., Lindner R., Heck S., Skowasch D.; Posterbeitrag Internationaler Kongress der European Respiratory Society (ERS), Barcelona, Spanien 09-2022

Identification of Severe, Uncontrolled Asthma Patients in Clinical Practice: An Enriched Methodology Based Study; Christoph Schöbel, Kerstin Defosse, Stefan Heindl, Frank Kanniess, Matthias Krüll, Fabian Pott, Olaf Schmidt, Thomas Schultz, Marek Lommatzsch; Präsentation DGP Kongress Düsseldorf, 03-2023

Identification of COPD patients in clinical practice: An enriched methodology-based study; Olaf Schmidt, Christoph Schöbel, Claus Franz Vogelmeier, Frank Kanniess, Matthias Krüll, Thomas Schultz, Katayoon Safavi, Charles Christian Adarkwah, Melanie Abram, Kerstin Defosse, Stefan Heindl; Präsentation DGP Kongress Düsseldorf, 03-2023

Effect of electronic MOnitoring and FEEdback on adherence to controller and rescue medication use in patients with asthma; eMOFEE trial design; Schultz T, Sebert M, Lähelmä S, Schmidt O; Posterbeitrag Präsentation EAACI Congress Hamburg, 06-2023

Fachbuch
Digital Medicine
Bringing Digital Solutions to Medical Practice;
Chapter 26; Digital Medicine in Pulmonary Medicine; O. Schmidt